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SGCD Polyclonal Antibody, 20ul Insect Expression This protein has a role

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SGCD Polyclonal Antibody, 20ul Insect Expression This protein has a roleThe protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin glycoprotein complex (DGC). DGC forms a link between the F actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb girdle muscular dystrophy and dilated cardiomyopathy.

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Description

This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER

Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides

Multiple alternatively spliced transcript variants have been described

involved in calcium binding and microtubule stabilization

The protein has been shown to bind to the 5

SGCD Polyclonal Antibody, 20ul Insect Expression This protein has a roleThe protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin glycoprotein complex (DGC). DGC forms a link between the F actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb girdle muscular dystrophy and dilated cardiomyopathy.

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