PAPP1 Polyclonal Antibody, 100ul Glassware Sets The function of this gene

The function of this gene product is not known

The protein encoded by this gene is a Rab-GTPase-activating protein| and contains two phopshotyrosine-binding domains (PTB1 and PTB2)| a calmodulin-binding domain (CBD)| a Rab-GTPase domain| and multiple AKT phosphomotifs

The encoded protein is found in the cytoplasm as part of a multiprotein complex

the CDK inhibitor isoforms and the ARF product encoded by this gene

DEAH-box helicase 8 contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins

PAPP1 Polyclonal Antibody, 100ul Glassware Sets The function of this geneThis gene encodes a secreted metalloproteinase which cleaves insulin like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.