TBP Polyclonal Antibody, 20ul Biochemical Reagents The alternative splicing demonstrated in

The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain

Transgenic mice overexpressing this gene exhibit defects in testis

The active form of the protein is found extracellularly as a homodimer

Methylation of the genes promoter has been associated with several cancer types

This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway

TBP Polyclonal Antibody, 20ul Biochemical Reagents The alternative splicing demonstrated inInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA binding protein (TBP) and a group of