RUNX1 Polyclonal Antibody, 100ul[BT-AP08057] Liquid Storage Consumables RIMKLA contains one ATP-grasp domain

RIMKLA contains one ATP-grasp domain and binds two manganese ions per subunit

May act as a transcriptional repressor (Potential)

which localizes to both sides of the nuclear pore complex at interphase

subcellular location:Also cytoplasmic and nuclear

Hormones that elevate intracellular cAMP increase I-1 activity in many tissues

RUNX1 Polyclonal Antibody, 100ul[BT-AP08057] Liquid Storage Consumables RIMKLA contains one ATP-grasp domainCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by CBF2alpha (runt related transcription factor 1, RUNX1) represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three