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HAP1 Polyclonal Antibody, 50ul Cell Culture Dishes Contains 4 VWFD domains

SKU: 7998038954

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HAP1 Polyclonal Antibody, 50ul Cell Culture Dishes Contains 4 VWFD domainsHuntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase

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Description

Contains 4 VWFD domains

tissue specificity:Expressed in the brain

The protein belongs to the S12P family of ribosomal proteins

This protein controls cell cycle arrest and apoptosis by regulating p21| a cell cycle regulator| and the tumor suppressor protein p53

The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade

HAP1 Polyclonal Antibody, 50ul Cell Culture Dishes Contains 4 VWFD domainsHuntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase

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