Spindlin-1 Polyclonal Antibody, 50ul sgRNA Oligos Decreased expression of this receptor

Decreased expression of this receptor has been observed in various cancers

and may play a role in neural tube development and muscle differentiation

The pleckstrin homology and RhoGEF domain containing G4 encoded by PLEKHG4 can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus

enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

plays a role in inflammatory responses through binding to the receptors CCR1

Spindlin-1 Polyclonal Antibody, 50ul sgRNA Oligos Decreased expression of this receptorSphingolipid transporter (By similarity). May be involved in necrotic or autophagic cell death.