Trk B Polyclonal Antibody, 50ul[BT-AP09215] Antibody Development Mutations in this gene have

Mutations in this gene have been associated with autosomal dominant spastic paraplegia 6

An important paralog of this gene is CDK14

This gene encodes a member of the DNA mismatch repair MutS family

cell adhesion is stronger on the PC membrane and its higher pore density enables easier exchange of transmembrane substances

Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin

Trk B Polyclonal Antibody, 50ul[BT-AP09215] Antibody Development Mutations in this gene haveNTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.