Rat Lactoylglutathione Lyase, GLO1 ELISA Kit, 96T Human Genome Knockout Libraries the protein-glutamine gamma-glutamyltransferase 2 is

the protein-glutamine gamma-glutamyltransferase 2 is the autoantigen implicated in celiac disease

The protein encoded by this gene is an omega class glutathione S-transferase (GST)

and thus it may function in mitosis

and maps to human chromosome 17q21

It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed: 12598906)

Rat Lactoylglutathione Lyase, GLO1 ELISA Kit, 96T Human Genome Knockout Libraries the protein-glutamine gamma-glutamyltransferase 2 isCatalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S lactoylglutathione. Involved in the regulation of TNF induced transcriptional activity of NF kappa B (By similarity).