Neu Polyclonal Antibody, 20ul[BT-AP05906] Multi-Layer Cell Culture System The protein localizes to centrosomes

The protein localizes to centrosomes during interphase

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which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c

They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling

The growth factor receptor bound protein 2 encoded by GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains

Neu Polyclonal Antibody, 20ul[BT-AP05906] Multi-Layer Cell Culture System The protein localizes to centrosomesERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those