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ERAP2 Polyclonal Antibody, 20ul sgRNA Library Construction The protein is an E3

SKU: 78493697924

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ERAP2 Polyclonal Antibody, 20ul sgRNA Library Construction The protein is an E3This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on

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Description

The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins

The protein has a preference for binding single stranded DNA and RNA

A transcribed pseudogene of this gene has been identified on chromosome 15

Belongs to the CAS family

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B

ERAP2 Polyclonal Antibody, 20ul sgRNA Library Construction The protein is an E3This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on

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