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TAP Polyclonal Antibody, 50ul Drug Development and Evaluation Disruption of this gene in

SKU: 78347571504

4.3
PLN185.00 PLN234.00

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TAP Polyclonal Antibody, 50ul Drug Development and Evaluation Disruption of this gene inNXF1 is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP type RNA binding domain (RBD), 4 leucine rich repeats (LRRs), a nuclear transport factor 2 (NTF2) like domain that allows heterodimerization with NTF2 related export protein 1 (NXT1), and a ubiquitin associated domain that mediates interactions with nucleoporins. The LRRs and NTF2 like domains are required for export

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Description

Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation

An important paralog of this gene is ENTHD1

ALK/SQSTM1 (chromosome 5)

Actin alpha cardiac muscle 1/Actin alpha skeletal muscle/Actin aortic smooth muscle/Actin gamma-enteric smooth muscle encoded by ACTC1 belongs to the actin family which is comprised of three main groups of actin isoforms

and histone acetyltransferase domain

TAP Polyclonal Antibody, 50ul Drug Development and Evaluation Disruption of this gene inNXF1 is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP type RNA binding domain (RBD), 4 leucine rich repeats (LRRs), a nuclear transport factor 2 (NTF2) like domain that allows heterodimerization with NTF2 related export protein 1 (NXT1), and a ubiquitin associated domain that mediates interactions with nucleoporins. The LRRs and NTF2 like domains are required for export

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