Filamin 1(Phospho Ser2152) Polyclonal Antibody, 20ul Enzyme Activity Assays that are zinc-dependent enzymes capable

that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction

form a cytokine receptor gene cluster in a region mapped to chromosome 2q12

and cortical function

This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain

while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1

Filamin 1(Phospho Ser2152) Polyclonal Antibody, 20ul Enzyme Activity Assays that are zinc-dependent enzymes capableThe protein encoded by this gene is an actin binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias