Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation GO annotations related to this

GO annotations related to this gene include G-protein coupled receptor activity

This magnesium-binding protein forms homodimers and is located in the cytoplasm

Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C

It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells

including breast and ovarian tumors

Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation GO annotations related to thisRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.