LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 50ul Pasteur Pipets The nuclear-encoded DNA pol γ

The nuclear-encoded DNA pol γ is the only DNA polymerase required for the replication of the mitochondrial DNA

Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863

or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL

This enzyme can also transfer acyl CoA to retinol

this protein is predominantly expressed in the sebaceous gland of the skin

LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 50ul Pasteur Pipets The nuclear-encoded DNA pol γThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative