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ASPM Polyclonal Antibody, 20ul Sample Library Tubes some protein coding and one

SKU: 76343290211

4.5
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ASPM Polyclonal Antibody, 20ul Sample Library Tubes some protein coding and oneThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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Description

some protein coding and one non-protein coding

The encoded protein binds to Bcl-2 and possesses the BH3 domain

|subunit:Interacts with CBP| MYOCD| SIRT1| SRF and YWHAZ

Several transcript variants encoding different isoforms have been found for NCOA3

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain| a DHR-2 (CZH-2) domain and an SH3 domain

ASPM Polyclonal Antibody, 20ul Sample Library Tubes some protein coding and oneThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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