MLK3(Phospho Thr277+Ser281) Rabbit Polyclonal Antibody, 100ul Cell Screening and Imaging Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been reported

Mutations in this gene result in autosomal recessive spastic paraplegia

This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF)

SOX6 (SRY-box 6) encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA

The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds

MLK3(Phospho Thr277+Ser281) Rabbit Polyclonal Antibody, 100ul Cell Screening and Imaging Multiple alternatively spliced transcript variantsThe protein encoded by this gene is a member of the serine threonine kinase family. This kinase contains a SH3 domain and a leucine zipper basic motif. This kinase preferentially activates MAPK8 JNK kinase and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate and activates IkappaB kinase alpha and beta and is found to be involved in the transcription activity of NF kappaB mediated by Rho family GTPases