MARCH2 Polyclonal Antibody, 50ul Glassware Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding different isoforms have been described for MED23

This gene is expressed in kidney and brain

It is a human homolog of the E

This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination

CEP57 (centrosomal protein 57) encodes a cytoplasmic protein called Translokin

MARCH2 Polyclonal Antibody, 50ul Glassware Several alternatively spliced transcript variantsMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.