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Angiomotin-L1 Polyclonal Antibody, 100ul Shaker&Mixing Some of the isoforms contain

SKU: 75969836651

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Angiomotin-L1 Polyclonal Antibody, 100ul Shaker&Mixing Some of the isoforms containAngiomotin like protein 1 encoded by AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.

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Description

Some of the isoforms contain regions of similarity to beta-defensins| a family of antimicrobial peptides

Members of the WIPI subfamily of WD40 repeat proteins| such as WIPI2| have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al

which incorporates synthetic genotyping (Synotype) alongside Genotype and Phenotype

a heterotrimeric molecule

The gamma subunits contain the active site of the enzyme| whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation

Angiomotin-L1 Polyclonal Antibody, 100ul Shaker&Mixing Some of the isoforms containAngiomotin like protein 1 encoded by AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.

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