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PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07143] Molecular Sciences This hormone stimulates the secretion

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PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07143] Molecular Sciences This hormone stimulates the secretionPhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1

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Description

This hormone stimulates the secretion of bile and bicarbonate in the duodenum

Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene

Mutations in this gene cause Steel syndrome

It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs)

and acts as a decoy receptor that inhibits the activity of its ligands

PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07143] Molecular Sciences This hormone stimulates the secretionPhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1

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