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DEN1A Rabbit Polyclonal Antibody, 100ul Antibodies also known as glutamate-aspartate transport

SKU: 75744246441

4.3
SEK141.00 SEK178.00

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DEN1A Rabbit Polyclonal Antibody, 100ul Antibodies also known as glutamate-aspartate transportClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1A function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010

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Description

also known as glutamate-aspartate transport defect

This secreted protein undergoes a complex proteolytic maturation

Alternatively spliced transcript variants encoding multiple isoforms have been observed for CASP7

increased susceptibility to rheumatoid arthritis

A pseudogene of this gene is found on chromosome 16

DEN1A Rabbit Polyclonal Antibody, 100ul Antibodies also known as glutamate-aspartate transportClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1A function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010

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