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Raf-1(Phospho Ser621) Polyclonal Antibody, 100ul Gloves MIM 151460)

SKU: 75247589370

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Raf-1(Phospho Ser621) Polyclonal Antibody, 100ul Gloves MIM 151460)This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

MIM 151460)

while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site

The protein may play an important role in the epigenetic control of chromatin structure and gene expression

Peripherin is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin

MIM 165390)

Raf-1(Phospho Ser621) Polyclonal Antibody, 100ul Gloves MIM 151460)This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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