STAU2 Rabbit Polyclonal Antibody, 20ul Measuring Instruments The GRLF1 enhances the homologous

The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression

The encoded protein is located in the nucleus

Several genome-wide association studies have implicated the region around this gene to be involved in breast cancer and bone mineral density

The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein

In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL)

STAU2 Rabbit Polyclonal Antibody, 20ul Measuring Instruments The GRLF1 enhances the homologousStaufen homolog 2 is a member of the family of double stranded RNA (dsRNA) binding proteins involved in the transport and or localization of mRNAs to different subcellular compartments and or organelles. These proteins are characterized by the presence of multiple dsRNA binding domains which are required to bind RNAs having double stranded secondary structures. Staufen homolog 2 shares 48. 5% and 59. 9% similarity with drosophila and human staufen