EGFR(Phospho Thr693) Polyclonal Antibody, 50ul Custom DNA Oligos Interacts with LCP2 and ZAP70

Interacts with LCP2 and ZAP70

Transcripts for CD44 undergo complex alternative splicing that results in many functionally distinct isoforms

Its two SH3 domains direct complex formation with proline-rich regions of other proteins

Overexpression increases MET activation and promotes invasive growth

where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development

EGFR(Phospho Thr693) Polyclonal Antibody, 50ul Custom DNA Oligos Interacts with LCP2 and ZAP70The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.