WBS22 Rabbit Polyclonal Antibody, 100ul Custom DNA Oligos Genetic variation at this locus

Genetic variation at this locus has been associated with a range of behavioral phenotypes

nucleocytoplasmic transport of snRNAs and intranuclear transport between compartments of snoRNAs

It is expressed at a high level in fibroblast cells

and activation of transcription

Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids

WBS22 Rabbit Polyclonal Antibody, 100ul Custom DNA Oligos Genetic variation at this locusThis gene encodes a protein containing a nuclear localization signal and an S adenosyl L methionine binding motif typical of methyltransferases suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11. 23. Alternatively spliced transcript variants have been found.