Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller Mutations in this gene have

Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)| which involves increased risk of cancers including malignant mesothelioma| uveal melanoma and cutaneous melanoma

This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19

Demethylates both di- and trimethylated H3 'Lys-9' residue

This powerful kit enables you to accurately measure human IL-1β levels and maximize stability with proper storage at 2-8℃

Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller Mutations in this gene haveThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.