TBX15/18 Polyclonal Antibody, 100ul ssDNA Synthesis Mutations in CUBN may play

Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia

which plays a role in ribosomal gene transcription

This gene encodes a member of the tubulin superfamily

Based on sequence comparison

This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies

TBX15/18 Polyclonal Antibody, 100ul ssDNA Synthesis Mutations in CUBN may playTBX18 codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA binding T box domain and is divided into five sub families based on sequence conservation in this domain. The T box transcription factor TBX18 belongs to the vertebrate specific Tbx1 sub family. The protein acts as a transcriptional repressor by antagonizing