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CCD50 Rabbit Polyclonal Antibody, 100ul Protein Research with high affinity

SKU: 74851133556

4.5
PLN123.75 PLN153.75

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CCD50 Rabbit Polyclonal Antibody, 100ul Protein Research with high affinityThis gene encodes a soluble, cytoplasmic, tyrosine phosphorylated protein with multiple ubiquitin interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule based structures. This protein may also function as a negative regulator of NF kB signaling and as an

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Description

with high affinity

It also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner

which are localized to 19q13

This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly

IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al

CCD50 Rabbit Polyclonal Antibody, 100ul Protein Research with high affinityThis gene encodes a soluble, cytoplasmic, tyrosine phosphorylated protein with multiple ubiquitin interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule based structures. This protein may also function as a negative regulator of NF kB signaling and as an

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