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MSH2 Monoclonal Antibody, 100ul Sampling Tubes The coding sequence of this

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MSH2 Monoclonal Antibody, 100ul Sampling Tubes The coding sequence of thisThis locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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Description

The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units

The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy

Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection

tissue specificity:Expressed predominantly in lung

DFF becomes activated when DFFA is cleaved by caspase-3

MSH2 Monoclonal Antibody, 100ul Sampling Tubes The coding sequence of thisThis locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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