CTNL1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Alternative splicing results in a

Alternative splicing results in a multitude of transcript variants

This gene is intronless and is mapped to 1p32-p31

Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal

This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family

Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2

CTNL1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Alternative splicing results in aMay modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction: Down regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,Belongs to the vinculin alpha catenin family.,subunit: Interacts with ARHGEF1.,tissue specificity: Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,