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Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes This protein has also been

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Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes This protein has also beenThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation

KCNF1 is intronless and expressed in all tissues tested

It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle

disease:Defects in CDKN2A are a cause of Li-Fraumeni syndrome (LFS)

The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules

Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes This protein has also beenThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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