SPT16 Polyclonal Antibody, 100ul Modified Oligos Mutations in this gene are

Mutations in this gene are a cause of 3M syndrome-3 (3M3)

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skeletal muscle and pancreas

which is a member of the phosphorylase b kinase regulatory subunit family

This gene is clustered with related family members on chromosome 5q33

SPT16 Polyclonal Antibody, 100ul Modified Oligos Mutations in this gene areTranscription of protein coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A H2B to effect nucleosome disassembly and transcription elongation. FACT is