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CALCR Polyclonal Antibody, 100ul Lysosome The receptors are seven-pass transmembrane

SKU: 74485856564

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CALCR Polyclonal Antibody, 100ul Lysosome The receptors are seven-pass transmembraneThis gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane spanning G protein coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript

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Description

The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways

so that the gene pair shares a common promoter

The encoded protein (B-cell receptor-associated protein 31) is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis

During normal growth conditions

where it catalyzes the transfer of galactose from UDP-galactose to substrates containing a terminal beta-linked galactose moiety

CALCR Polyclonal Antibody, 100ul Lysosome The receptors are seven-pass transmembraneThis gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane spanning G protein coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript

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