NEK2 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds The encoded protein may play

The encoded protein may play a role in breast cancer proliferation and chemoresistance

where it is required for transcription

BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways

The encoded protein also promotes tumorigenesis through an angiogenic activity

allowing microhomologous sequences in the overhangs to form base pairs

NEK2 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds The encoded protein may playThis gene encodes a serine threonine protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C termini have been noted for this gene.