MGST3 Polyclonal Antibody, 100ul Protein Modification Mutations in this gene are

Mutations in this gene are a cause of branchiootorenal syndrome type 2

Altered copy number and activity of this gene have been observed in a number of human cancers

The protein encoded by this gene belongs to the Ser/Thr protein kinase family

The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain

In contrast

MGST3 Polyclonal Antibody, 100ul Protein Modification Mutations in this gene areMGST3 encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. MGST3 encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione dependent peroxidase activity