CPI-17(Phospho Thr38) Polyclonal Antibody, 100ul Peptide Synthesis The LIM/double zinc-finger motif found

The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation

PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway

which localize to the mitochondrial matrix

and re-sealable bag

Methylation of the CpG island leads to transcriptional silencing of this gene

CPI-17(Phospho Thr38) Polyclonal Antibody, 100ul Peptide Synthesis The LIM/double zinc-finger motif foundThe protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.