TAF II p135/p105 Polyclonal Antibody, 50ul Enzymes Increased expression of ABCC12 is

Increased expression of ABCC12 is associated with breast cancer

The protein encoded by this gene is an inositol 1|4|5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain

and there is an inverse correlation between the expression of this protein and miR29 levels

The parkin co-regulated gene protein forms a large molecular complex with chaperones| including heat shock proteins 70 and 90| and chaperonin components

Several alternatively spliced transcript variants encoding different isoforms of this gene have been described

TAF II p135/p105 Polyclonal Antibody, 50ul Enzymes Increased expression of ABCC12 isInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA binding protein (TBP) and a group of