PCP Polyclonal Antibody, 50ul[BT-AP12851] Cell Senescence Mutations in this gene are

Mutations in this gene are a cause of spastic ataxia 2| autosomal recessive

and cell death

Alternative splicing of this gene results in several transcript variants encoding different isoforms

3-BPG) to 2-phosphoglycerate

This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele

PCP Polyclonal Antibody, 50ul[BT-AP12851] Cell Senescence Mutations in this gene areThis gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C terminal amino acids linked to proline in peptides such as angiotension II, III and des Arg9 bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to