Desmin Monoclonal Antibody(1B12), 100ul Buffer Solutions 22 µm PTFE hydrophobic

22 µm PTFE hydrophobic

It plays a negative regulatory role in the Ras-Raf1-MAPK pathway| and knockout mice have been shown to develop spontaneous tumors| suggesting a role as a tumor suppressor gene

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family

The specific function of this gene has not yet been determined| however

Defects in PEX3 are a cause Zellweger syndrome (ZWS)

Desmin Monoclonal Antibody(1B12), 100ul Buffer Solutions 22 µm PTFE hydrophobicThis gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.