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HtrA2 Polyclonal Antibody, 100ul[BT-AP04279] Pipette Filler Mutations in this gene result

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HtrA2 Polyclonal Antibody, 100ul[BT-AP04279] Pipette Filler Mutations in this gene resultHTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear

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Description

Mutations in this gene result in multiple epiphyseal dysplasia

It binds to integrins of type CD11a / CD18

This gene was mapped to 17q21

Lambda 5 (also called Immunoglobulin lambda-like polypeptide 1 or CD179b antigen) and VpreB comprise the surrogate light chain of the pre-B cell receptor complex

protecting cells from oxidative stress

HtrA2 Polyclonal Antibody, 100ul[BT-AP04279] Pipette Filler Mutations in this gene resultHTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear

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