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NDUB3 Polyclonal Antibody, 50ul Gene Editing Thrombospondin family members are adhesive

SKU: 73107511008

4.2
USD185.00 USD229.00

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NDUB3 Polyclonal Antibody, 50ul Gene Editing Thrombospondin family members are adhesiveThis gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein.

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Description

Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases| and contains a C-terminal domain unique from other RIP family members

PTM:Phosphorylation of Thr-35 is required for activity

Six alternative splice variants have been identified

|subunit:3 different light chains| LC1| LC2 and LC3| can associate with MAP1A and MAP1B proteins

NDUB3 Polyclonal Antibody, 50ul Gene Editing Thrombospondin family members are adhesiveThis gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein.

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