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p47-phox(Phospho Ser370) Polyclonal Antibody, 20ul Cryogenic Vials GAK is an association partner

SKU: 73063809863

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PLN111.00 PLN157.00

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p47-phox(Phospho Ser370) Polyclonal Antibody, 20ul Cryogenic Vials GAK is an association partnerThe protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

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Description

GAK is an association partner of cyclin G and CDK5

and germinal center formation

and is a receptor for C-C type chemokines

It has been also shown to play an important role in the proliferation and differentiation of B cells

Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

p47-phox(Phospho Ser370) Polyclonal Antibody, 20ul Cryogenic Vials GAK is an association partnerThe protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

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