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Shb Polyclonal Antibody, 50ul[BT-AP08286] Custom RNA Oligos Mutations in RAN disrupt DNA

SKU: 73023406352

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Shb Polyclonal Antibody, 50ul[BT-AP08286] Custom RNA Oligos Mutations in RAN disrupt DNAThe SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain containing proteins to tyrosine phosphorylated sites, an event that can trigger a protein protein interaction cascade which may ultimately effect gene expression and cellular function.

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Description

Mutations in RAN disrupt DNA synthesis

suggesting that it may also bind calcium

The aminoacyl tRNA synthetase complex interacting multifunctional protein 1 encoded by AIMP1 is a cytokine that is specifically induced by apoptosis

This gene and the WNT6 gene are clustered in the chromosome 2q35 region

This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a

Shb Polyclonal Antibody, 50ul[BT-AP08286] Custom RNA Oligos Mutations in RAN disrupt DNAThe SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain containing proteins to tyrosine phosphorylated sites, an event that can trigger a protein protein interaction cascade which may ultimately effect gene expression and cellular function.

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