KLF8 Polyclonal Antibody, 100ul Deep Well Plates ADAM metallopeptidase with thrombospondin type

ADAM metallopeptidase with thrombospondin type 1 motif 1 encoded by ADAMTS1 contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity

Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Bacterial invasion of epithelial cells

This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins

This gene encodes a member of the ETS family of transcription factors

and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules

KLF8 Polyclonal Antibody, 100ul Deep Well Plates ADAM metallopeptidase with thrombospondin typeKLF8 encodes Kruppel like factor 8 which is a member of the Sp KLF family of transcription factors. Members of this family contain a C terminal DNA binding domain with three Kruppel like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.