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CREB-1(Phospho Ser133) Polyclonal Antibody, 50ul Immuno Plates MARCH8 induces the internalization of

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CREB-1(Phospho Ser133) Polyclonal Antibody, 50ul Immuno Plates MARCH8 induces the internalization ofThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

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Description

MARCH8 induces the internalization of several membrane glycoproteins (Goto et al

Alternative splicing results in multiple transcript variants of AXL

The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1

P2RY8 is moderately expressed in undifferentiated HL60 cells

A related protein interacts with calcium/calmodulin-dependent serine protein kinase (CASK)

CREB-1(Phospho Ser133) Polyclonal Antibody, 50ul Immuno Plates MARCH8 induces the internalization ofThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

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