Tau(Phospho Ser262) Polyclonal Antibody, 100ul Immune Repertoire Sequencing Was initially reported to contain

Was initially reported to contain ARM repeats (PubMed:11386760)

The active| hypophosphorylated form of the protein binds transcription factor E2F1

The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins

It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation

It is very conserved in evolution

Tau(Phospho Ser262) Polyclonal Antibody, 100ul Immune Repertoire Sequencing Was initially reported to containThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,