SSH3 Polyclonal Antibody, 100ul Proteases Mutations in this gene are

Mutations in this gene are one cause of cerebral cavernous malformations

subunit:Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1

It encodes a zinc finger protein that can bind to retinoblastoma protein| estrogen receptor| and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene

NEFH encodes the heavy neurofilament protein

It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines

SSH3 Polyclonal Antibody, 100ul Proteases Mutations in this gene areThe ADF (actin depolymerizing factor) cofilin family (see MIM 601442) is composed of stimulus responsive mediators of actin dynamics. ADF cofilin proteins are inactivated by kinases such as LIM domain kinase 1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF cofilin proteins in vivo.