ARHGAP18 Polyclonal Antibody, 50ul Liquid Handling ＆Storage leading to further diversity and

leading to further diversity and potential for specialization

Studies in rat indicate that the protein is translated from a non-AUG translation initiation site

Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation

Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression

Three alternatively spliced variants encoding different isoforms have been described for this gene

ARHGAP18 Polyclonal Antibody, 50ul Liquid Handling ＆Storage leading to further diversity andARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).