PIG3 Polyclonal Antibody, 100ul Funnels The encoded protein is expressed

The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains

and has been found to be epigenetically silenced in various cancers

The expression of this protein can be induced by Epstein-Barr virus (EBV)

It has been shown to bind and activate the ILST/gp130 receoptor

The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination

PIG3 Polyclonal Antibody, 100ul Funnels The encoded protein is expressedTumor protein p53 inducible protein 3 encoded by TP53I3 is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. TP53I3 is induced by the tumor suppressor p53 and is thought to be involved in p53 mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate