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CD55 Polyclonal Antibody, 20ul[BT-AP02480] Recombinant Protein Expression Alternative splicing in the coding

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CD55 Polyclonal Antibody, 20ul[BT-AP02480] Recombinant Protein Expression Alternative splicing in the codingKRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal

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Description

Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms

intercellular conduits that directly connect the cytoplasms of contacting cells

A number of alternatively spliced transcript variants have been described

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Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region

CD55 Polyclonal Antibody, 20ul[BT-AP02480] Recombinant Protein Expression Alternative splicing in the codingKRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal

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