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TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters Core component of multiple SCF-like

SKU: 71044808536

4.7
PLN141.00 PLN174.00

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TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters Core component of multiple SCF-likeThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.

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Description

Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes

thereby improving efficiency

MBP is a useful affinity tag that can increase the expression level and solubility of the resulting tagged protein

The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing

KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif)

TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters Core component of multiple SCF-likeThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.

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